I have been running a pi-hole server at my home for almost a year. We have, at times, around thirty devices on our network, (thermostat (non-nest), several Google Home devices, numerous phones, 4 desktops, 4 laptops, 3 ipads, 1 TV, a chromecast/roku/firestick, a few smart receptacles, and a Xfinity modem) and sometimes the traffic is pretty neat to examine. Its interesting to see which devices phone home.
Whenever a necessary site is blocked it only takes a few seconds to whitelist it. I can also easily blacklist sites. The GUI is very easy to access and use. We have never had an issue with YouTube (YT premium) or anything else really, but occasionally a link will be blocked because of Google or other ad traffic. This has never happened with YT or any other streaming services.
One thing to remember is VPN traffic ignores the Pi-Hole server. Even when the router/computer/device DNS is set to use it. This has never been an issue for us, as only a handful of devices here are using VPN, but I suppose it could be under the right circumstances, but easily fixable.
Whenever a necessary site is blocked it only takes a few seconds to whitelist it. I can also easily blacklist sites. The GUI is very easy to access and use. We have never had an issue with YouTube (YT premium) or anything else really, but occasionally a link will be blocked because of Google or other ad traffic. This has never happened with YT or any other streaming services.
One thing to remember is VPN traffic ignores the Pi-Hole server. Even when the router/computer/device DNS is set to use it. This has never been an issue for us, as only a handful of devices here are using VPN, but I suppose it could be under the right circumstances, but easily fixable.